Moderna shares soar 100% on positive personalized cancer vaccine trial

Moderna shares surged as much as 100% in premarket trading after an experimental personalized cancer vaccine developed with Merck produced positive results in its first late-stage trial. Stock futures were little changed after the market ended the previous session lower. Global bond yields continued to rise, with the 30-year U.S. Treasury yield reaching another record and comparable German and French yields climbing to levels not seen in more than a decade. Tariff refunds boosted corporate earnings: Target said the refunds added $752 million to second-quarter net earnings and raised its full-year outlook, while Lowe’s said they increased earnings per share by 11 cents. Lowe’s nevertheless missed second-quarter revenue expectations and issued a tepid outlook, sending its shares down more than 3% before the open. Home Depot shares ended the prior session slightly lower despite beating Wall Street estimates, while Walmart is due to report earnings the following day. President Donald Trump said he would pause a planned 50% tariff on certain Canadian goods for three days while documents for a deal were finalized. The proposed duties would have applied to imports including hockey sticks and wine. Canadian Federation of Independent Business president Dan Kelly said the tariffs would have made products uneconomic to sell and could have halted members’ U.S. sales. As vehicle demand softens, dealerships are relying more on parts and service operations, whose average gross profit rose to $5 million in 2025 from $3.3 million in 2020, according to Kerrigan Advisors. Chain repair shops are nevertheless taking market share. American Airlines plans to add seatback screens to most of its narrow-body fleet beginning in 2028, reversing an earlier view that the displays were too costly and heavy. The cyclospora outbreak is also reshaping corporate lunch patterns and forcing salad companies to adjust their marketing.

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Moderna shares soar 100% on positive personalized cancer vaccine trial - CoinPost Terminal