The Buffalo Bills will visit the Houston Texans at NRG Stadium on Sunday, Sept. 13, at 1:00 p.m. ET to open the 2026 NFL season. Kalshi, a prediction market using event contracts tied to outcomes, prices Buffalo at a 52% chance of winning and Houston at 48%. The Bills are also priced at 49% to win by more than 1.5 points, while the game is priced at 49% to exceed 44.5 combined points. Both teams went 12-5 in 2025 and fell in the divisional round after winning their wild-card games. Buffalo lost to Denver in overtime, leading to Sean McDermott's firing after nine years and the promotion of longtime offensive coordinator Joe Brady to head coach. Josh Allen underwent offseason surgery for a broken bone in his right foot but enters Week 1 without limitations. Buffalo also added receiver DJ Moore and edge rusher Bradley Chubb. Houston ended the regular season on a nine-game winning streak, beat Pittsburgh in the wild-card round and then lost to New England in the divisional round. C.J. Stroud dealt with a shoulder injury and declining performance late in 2025, prompting Houston to reinforce its offensive line with free-agent tackle Braden Smith and trade acquisition guard Wyatt Teller. Offensive coordinator Nick Caley returns for a second season. Kalshi's 2026 market-implied power rankings place Buffalo third with a 39.6 Power Score and a 74% playoff qualification price, while Houston ranks sixth with a 35.5 Power Score and a 64% playoff price. The market's prices can change during the week before kickoff.