Wall Street's main indexes opened lower on Wednesday as rising crude prices and government bond yields weighed on investor sentiment. The Dow Jones Industrial Average fell 92.3 points, or 0.18%, to 51,771.41 at the open. The S&P 500 declined 2.7 points, or 0.03%, to 7,761.94, while the Nasdaq Composite dropped 30.8 points, or 0.11%, to 27,213.519. Investors were watching negotiations aimed at ending the Middle East conflict ahead of a high-stakes US-China summit. The report was written by Avinash P in Bengaluru and edited by Shinjini Ganguli.