The global Vendor Neutral Archive and PACS market was valued at USD 4.52 billion in 2025 and is projected to reach USD 11.57 billion by 2035, according to SNS Insider, representing a 9.85% CAGR from 2026 to 2035. The market supports the storage, access and exchange of medical imaging data across hospitals and diagnostic imaging centers in interoperable formats. PACS accounted for approximately 60.40% of the market in 2025, while cloud-based deployment held 54.60%. Cardiology was the largest application at 34.80%, hospitals represented 58.60% of end users, and North America led regional share with about 43.60%. Asia Pacific is forecast to grow fastest at a 12.80% CAGR. Demand is being driven by rising imaging volumes, cloud and hybrid migration, enterprise interoperability and healthcare digitization. AI-enabled diagnostics and radiomics represent opportunities, while implementation costs and the risks of migrating legacy imaging data remain obstacles.