US stock futures were muted early Wednesday as investors awaited negotiations to end the Middle East conflict and a high-stakes summit between President Donald Trump and Chinese President Xi Jinping. At 07:09 a.m. ET, Dow E-minis were down 22 points, or 0.04%, S&P 500 E-minis were up 1.25 points, or 0.02%, and Nasdaq 100 E-minis were down 33 points, or 0.11%. Oil remained below $100 a barrel after Saudi Arabia restarted operations along its East-West pipeline, easing immediate supply concerns. Mediators began US-Iran negotiations on the sidelines of the UN General Assembly, while markets awaited further updates. Xi’s September 23-25 U.S. state visit is expected to include discussions on extending last year’s trade truce, artificial intelligence regulation and US arms sales to Taiwan, as well as meetings with executives from General Motors, Meta, Apple, Amazon and Tesla. The Nasdaq recorded its first intraday record high since early June on Tuesday, supported by optimism over artificial intelligence and strong reception for Meta’s AI assistant Muse. Investors were also monitoring financial-sector weakness, General Mills’ 1.1% gain after beating first-quarter sales estimates, S&P Global’s September Purchasing Managers’ Index and remarks from Fed Governor Michael Barr. Traders were pricing a 50% chance of at least a 25-basis-point rate increase next month, according to CME Group’s FedWatch Tool.