The global knee replacement market was valued at $12.17 billion in 2025 and is projected to reach $17.81 billion by 2034, expanding at a 4.32% compound annual growth rate from 2026 to 2034, according to Maximize Market Research. Demand is being supported by rising knee osteoarthritis, rheumatoid arthritis, obesity, age-related joint degeneration, mobility impairment and procedure volumes. North America held the largest share in 2025, while Asia-Pacific is expected to record strong growth as healthcare infrastructure, expenditure, awareness and adoption of robotic and digital orthopedic technologies improve. Robotic-assisted surgery, AI-enabled planning, cementless and patient-specific implants, minimally invasive procedures, outpatient arthroplasty, smart implants and digital rehabilitation are reshaping care. High procedure costs, limited reimbursement, shortages of specialized surgeons and unequal access to advanced infrastructure remain constraints.