Insilico nominates ISM1354 GIPR drug candidate with 18-fold exposure advantage

Verifying
  • Insilico Medicine nominated ISM1354, an AI-driven GIPR antagonist candidate for obesity-related disorders.
  • ISM1354 achieved 75% to 104% oral bioavailability and at least 18-fold higher plasma exposure.
  • Insilico nominated 10 preclinical candidates during the first nine months of 2026.
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