Jim Cramer said the impact of higher interest rates is his biggest concern for the stock market, roughly two weeks after the Federal Reserve resumed raising borrowing costs. The Fed lifted its target range by a quarter point to 3.75% to 4% on September 16, its first increase since 2023, citing the need for a timelier return to its 2% inflation goal. Personal Consumption Expenditures (PCE) inflation eased to 3.4% in August but remained above target. Fed projections showed 16 of 18 participants expecting at least one more increase this year, while J.P. Morgan expects a December hike without a prolonged tightening cycle. Futures traders mostly anticipate no change on October 28, but CME FedWatch puts the odds of a higher range at 79.4% for December 9, with a 61.3% probability assigned to a quarter-point move to 4% to 4.25%. Rate-sensitive shares such as Home Depot have weakened, while the 10-year Treasury yield rose to about 5.24% on October 1 from roughly 4.16% at the start of 2026. The S&P 500 remains up about 12% in 2026, and Cramer said the coming earnings season should clarify how higher borrowing costs are affecting companies.