Mabwell to present Phase 2 9MW2821 data in triple-negative breast cancer at ESMO 2026

The biopharmaceutical company said an oral presentation will highlight Phase 2 results for its Nectin-4-targeting ADC in previously treated locally advanced or metastatic triple-negative breast cancer.

Summary

Mabwell said it will present Phase 2 clinical results for Bulumtatug Fuvedotin, also known as 9MW2821, at the 2026 European Society for Medical Oncology Annual Congress in Madrid. The oral presentation will cover patients with locally advanced or metastatic triple-negative breast cancer who were previously treated with Topoisomerase I inhibitor-based antibody-drug conjugates. The abstract, numbered 4640RO, is scheduled in the advanced-stage breast cancer session on October 26, 2026, from 10:15 a.m. to 11:45 a.m. local time, with Prof. ZHANG Jian of Fudan University Shanghai Cancer Center listed as presenter. Mabwell, listed in Shanghai and Hong Kong as 688062.SH and 02493.HK, describes itself as an innovation-driven biopharmaceutical company focused on oncology and aging-related diseases.

Terms & Concepts
  • antibody-drug conjugate: A targeted cancer therapy that links an antibody to a drug payload to deliver treatment to tumor cells.
  • Nectin-4-targeting ADC: An antibody-drug conjugate designed to bind the Nectin-4 protein on cancer cells.
  • triple-negative breast cancer: A breast cancer subtype that lacks three common receptors, limiting standard targeted treatment options.