The new India-based unit is designed for peptides, HPAPIs and other biomolecules, adding closed-loop processing, ISO Class 8 cleanliness and support for small-volume, high-potency batches.
Piramal Pharma Solutions has opened a new spray drying suite with Band 5 containment at its dedicated peptide development and manufacturing site in Turbhe, India, expanding its ability to formulate peptides, HPAPIs and other biomolecules. The company said the suite is built to handle complex formulation work that requires tight control over temperature, solvent conditions and particle properties, which are important for peptides because they can be unstable during processing. Spray drying converts liquid formulations into dry powders in a single step, a method used to improve bioavailability, manage particle size and protect sensitive compounds while helping scale-up. The closed-loop unit has its own air handling units, nitrogen supply and control systems, along with specialized HVAC, airlocked entry and exit points, operator isolation and a dedicated cleaning area. Piramal Pharma Solutions said the processing area meets ISO Class 8 cleanliness standards, the unit supports feed rates of up to 1 liter per hour, and it can process highly concentrated solutions with up to 30% water content. Under optimal conditions, the suite can also be used for low-volume small-molecule formulations. Dr. Jordi Bacardit, Global Technical Lead on Peptides and Member of the Science Collective at PPS, said the expansion would help partners develop stable, high-quality peptide formulations. The company said the investment strengthens its position as a partner for a broad range of therapeutic areas as demand for peptides and other complex molecules grows.