Creative Medical gets U.S. patent allowance for type 1 diabetes immunotherapy

The notice of allowance broadens protection for Creative Medical's exosome-based diabetes program, while shares more than doubled Thursday afternoon after the announcement.

Summary

Creative Medical Technology Holdings Inc. said it received a Notice of Allowance from the U.S. Patent and Trademark Office for a patent application titled "Suppression of Diabetes Using Exosomes From Stem Cell Programmed Myeloid Cells," expanding intellectual property protection around its MyeloCelz platform and broader type 1 diabetes program. The clinical-stage biotechnology company said the cell-free technology uses stem-cell-programmed myeloid cells to induce immune tolerance and halt autoimmune destruction of insulin-producing pancreatic beta cells. Management said the allowance adds to a portfolio of about 60 issued patents and pending applications. Shares were up 104.67% at $1.36 on Thursday afternoon.

Terms & Concepts
  • Exosomes: Small vesicles released by cells that can carry biological signals and are being studied for therapeutic use.
  • Notice of Allowance: A U.S. patent office notice indicating a patent application has been approved and is expected to issue.
  • Immune tolerance: A state in which the immune system does not attack specific cells or tissues, a key goal in autoimmune disease treatment.