Polymarket has secured approval from the U.S. Commodity Futures Trading Commission (CFTC) to reenter the U.S. market through its acquisition of QCX, a U.S.-registered derivatives exchange. The decision follows a series of strategic moves including a $112 million acquisition, major institutional investments, and high-profile board appointments, and sets the stage for Polymarket to resume offering compliant prediction contracts to U.S. users after a 2022 settlement. Despite regulatory challenges, including allegations of market manipulation and restrictions in several international markets, Polymarket continues to expand, processing over $6 billion in bets in the first half of 2025 alone.