On October 17, 2025, U.S. stock indices opened mixed, with the Dow Jones up 0.05%, S&P 500 down 0.18%, and Nasdaq down 0.38%. Crypto-related stocks mostly fell, including Circle (-2%), Coinbase (-1.6%), Bitmine Immersion (-2.3%), SharpLink Gaming (-3.8%), and Bit Digital (-3.5%). However, MicroStrategy (MSTR) gained 0.58%.